Assessment of macroprolactinemia by polyethylene glycol precipitation method
نویسندگان
چکیده
منابع مشابه
Polyethylene glycol precipitation as a screening method for macroprolactinemia.
To the Editor: Vieira et al. (1) used the Wallac Delfia immunofluorometric assay to demonstrate that macroprolactin is a common cause of apparent hyperprolactinemia, and this confirms our experience (2) and that of others (3). However, their data validating the polyethylene glycol (PEG) precipitation as a screening method for detecting macroprolactinemia are substantially different than ours (2...
متن کاملExtensive experience and validation of polyethylene glycol precipitation as a screening method for macroprolactinemia.
Serum human prolactin (PRL) is heterogeneous in molecular size, with the 23-kDa monomer being the predominant form in healthy subjects and patients with prolactinomas. From the point of view of molecular size, other circulating forms include the 50-kDa dimer (big-PRL) and the 150to 170-kDa form (big-big-PRL, or macroprolactin) (1). Recent publications have associated asymptomatic hyperprolactin...
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ژورنال
عنوان ژورنال: Revista Portuguesa de Endocrinologia, Diabetes e Metabolismo
سال: 2014
ISSN: 1646-3439
DOI: 10.1016/j.rpedm.2014.03.005